Drug Details
Drug Name(s) - A.P.L.
FDA Application No. - (NDA) 017055
Active Ingredient(s) -GONADOTROPIN, CHORIONIC
Company - FERRING
Original Approval or Tentative Approval Date - December 13, 1974
Chemical Type - 5 New formulation or new manufacturer
Review Classification - S Standard review drug
Drug Name(s) - A.P.L.
FDA Application No. - (NDA) 017055
Active Ingredient(s) -GONADOTROPIN, CHORIONIC
Company - FERRING
Original Approval or Tentative Approval Date - December 13, 1974
Chemical Type - 5 New formulation or new manufacturer
Review Classification - S Standard review drug
Uses
This medication is a hormone used in boys (before puberty) to cause the normal dropping of the testicles into the scrotum. It is also used in certain boys to help with normal sexual development. It works by causing the testes to release male sexhormones (e.g., testosterone).
This medication is also used in women to treat fertility problems. It is given after finishing another medication (menotropins) to cause the release of an egg (ovulation). It should not be used in women whose ovaries no longer make eggs properly (primary ovarian failure).
This medication has not been shown to be effective for weight loss and should not be used for this purpose.
How to use A.P.L. intramuscularThis medication is given by injection into a muscle by a health care professional. If you are giving this medication at home, learn all preparation and usage instructions for this product. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. If you have any questions about the use of this medication, ask your doctor or pharmacist.
The dosage is based on your age, weight, medical condition, and response to treatment.
For boys, use this medication usually 3 times a week or as directed by your doctor. For women, use this medication usually for 1 dose after finishing your menotropins treatment.
Use this medication regularly to get the most benefit from it. To help you remember, mark the day(s) on the calendar when you need to receive the medication.
This medication is a hormone used in boys (before puberty) to cause the normal dropping of the testicles into the scrotum. It is also used in certain boys to help with normal sexual development. It works by causing the testes to release male sexhormones (e.g., testosterone).
This medication is also used in women to treat fertility problems. It is given after finishing another medication (menotropins) to cause the release of an egg (ovulation). It should not be used in women whose ovaries no longer make eggs properly (primary ovarian failure).
This medication has not been shown to be effective for weight loss and should not be used for this purpose.
How to use A.P.L. intramuscularThis medication is given by injection into a muscle by a health care professional. If you are giving this medication at home, learn all preparation and usage instructions for this product. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. If you have any questions about the use of this medication, ask your doctor or pharmacist.
The dosage is based on your age, weight, medical condition, and response to treatment.
For boys, use this medication usually 3 times a week or as directed by your doctor. For women, use this medication usually for 1 dose after finishing your menotropins treatment.
Use this medication regularly to get the most benefit from it. To help you remember, mark the day(s) on the calendar when you need to receive the medication.
Side Effects
Headache, restlessness, tiredness, or pain at injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: swelling of the ankles/feet, mental/mood changes (e.g., depression, irritability), signs of early puberty in boys (e.g., facial/pubic hair, voice change, acne), pain/swelling of the breast (in boys).
For women, when this medication is used with menotropins to treat infertility, also tell your doctor right away if this unlikely but serious side effect occurs: abdominal pain/pressure/swelling.
For women, when this medication is used with menotropins to treat infertility, seek immediate medical attention if any of these rare but very serious side effects occur:chest pain, slurred speech, weakness on one side of the body, confusion.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash,itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, shortness of breath.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Headache, restlessness, tiredness, or pain at injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: swelling of the ankles/feet, mental/mood changes (e.g., depression, irritability), signs of early puberty in boys (e.g., facial/pubic hair, voice change, acne), pain/swelling of the breast (in boys).
For women, when this medication is used with menotropins to treat infertility, also tell your doctor right away if this unlikely but serious side effect occurs: abdominal pain/pressure/swelling.
For women, when this medication is used with menotropins to treat infertility, seek immediate medical attention if any of these rare but very serious side effects occur:chest pain, slurred speech, weakness on one side of the body, confusion.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash,itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, shortness of breath.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: early puberty (in boys), male sex hormone-dependant cancer (e.g., prostate cancer) in boys.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (e.g., congestive heart failure), kidney disease, seizures, asthma, migraine headaches.
This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away.
When this medication is used in females with menotropins to treat infertility, it may cause multiple births (e.g., twins, triplets).
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: early puberty (in boys), male sex hormone-dependant cancer (e.g., prostate cancer) in boys.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (e.g., congestive heart failure), kidney disease, seizures, asthma, migraine headaches.
This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away.
When this medication is used in females with menotropins to treat infertility, it may cause multiple births (e.g., twins, triplets).
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.